State Institution ‘The Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine‘

Innovative Technology for Treating Choroidal Melanoma Stages T1–T3

Science
25.06.2025

🎉 Achievements of staff of the Department of Ophthalmooncology of SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the National Academy of Medical Sciences of Ukraine"!

🔬 Our specialists—DMedSc Poliakova S.I., Professor Maletskii A.P., Cand. of Med. Sc. Chebotaryov Ye.P., Cand. of Med. Sc. Tsukanova I.V. and Drumi D.A. — have developed an innovative combined approach using transpupillary thermotherapy (810 nm) and brachytherapy Sr90/It90 for treating choroidal melanoma stages T1–T3. This method significantly enhances treatment effectiveness while preserving patients’ quality of life.

🩺 What's the essence of the approach?

The method consists of four sessions of transpupillary thermotherapy followed by brachytherapy, which increases tumor radiosensitivity and maximizes the impact on residual tumor cells.

✅ Key advantages compared to existing technologies:

• Improved effectiveness in treating choroidal melanoma stages T1–T3

• Enhanced radiosensitization effect of brachytherapy

• Additional impact on the remaining tumor after irradiation

• Treatment effectiveness of 92.5%

• Individualized parameter selection for each patient

💡 What’s new?

This is the first technique to implement daily thermotherapy for four days with customized laser power settings (200 to 1300 mW), ensuring high accuracy and patient safety.

📈 Results:

An increase in positive clinical outcomes, fewer complications, improved vision quality, and preservation of the eyeball.