INNOVATIONS IN THE FIGHT AGAINST RETINOBLASTOMA
Retinoblastoma is the most common highly malignant intraocular tumor in young children, accounting for about 4% of all malignant neoplasms in childhood. Late diagnosis, progressive growth, and the risk of metastasis make it extremely dangerous for a child’s life.
Specialists from the Department of Pediatric Ophthalmic Pathology of SI "The Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine", led by Professor Nadiia Fedorivna Bobrova, together with researchers from E.O.Paton Electric Welding Institute (Kyiv), have developed two innovative methods of enucleation for eyes affected by retinoblastoma using high-frequency electric current (HEC).
Thanks to the application of HEC in "cutting" and "welding" modes, the following results were achieved:
- Reduced intraoperative bleeding
- Prevention of tumor cell spread via the optic nerve and hematogenous pathways
- Maximum ablation precision during surgery
- Effective tumor removal, especially in cases with a high risk of dissemination
The surgeries were performed using the EK-300M1 device and specialized instruments of original design. All patients underwent surgery and postoperative recovery without complications. Adjuvant chemotherapy (with or without external radiation) was administered to 42 children.
In the long-term follow-up, no cases of orbital recurrence, intracranial growth, or brain metastases were recorded. All children achieved a good cosmetic outcome without deformities or scarring in the conjunctival cavity.
The use of HEC in retinoblastoma surgery marks a significant step in reducing complications, improving treatment outcomes, and enhancing the quality of life for young patients.