The main indicator for regulating the stabilization of the glaucomatous process remains intraocular pressure (IOP). During single visits, in cases of doubtful or borderline IOP, orthostatic tests are becoming relevant again in modern conditions.

Researchers from the Department of glaucoma and lens pathology of the State Institution “The Filatov Institute of Eye Diseases and Tissue Therapy of the National Academy of Medical Sciences of Ukraine,” MD, Prof. S.K. Dmitriev (head of the department), Ph.D., Senior Researcher O.A. Peretyagin, and junior researcher Yu.O. Tatarina, in their study, determined the dynamics and level of IOP fluctuations in patients with unstabilized primary open-angle glaucoma during orthostatic tests with an induction rebound tonometer.

A comprehensive ophthalmological study was conducted on 30 patients. IOP fluctuations were studied in 60 eyes. IOP fluctuations were measured with an induction rebound tonometer in the patient’s vertical position, then in the horizontal position at the 1st minute, 3rd minute, and 5th minute of the horizontal position.

It was found that in eyes with unstabilized glaucoma with slightly elevated pressure, IOP increased immediately or began to gradually increase from the 3rd or 5th minute of the horizontal position. The average IOP increase in eyes with unstabilized glaucoma was 4.1 mm Hg.

The study established that in unstabilized primary open-angle glaucoma, IOP increases from 2.7 to 8.0 mm Hg when the body is moved from a vertical to a horizontal position, either immediately or gradually over 5 minutes in the horizontal position, exceeding 21.0 mm Hg (the upper limit of normal for induction rebound tonometry).

Source: https://institut-filatova.com.ua/wp-content/uploads/2024/06/Tezy-FCh-2024.pdf 43